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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8441 | Lerisetron | 5-HT Receptor | |
Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity. | |||
T21629 | Loxapine | Dopamine Receptor , 5-HT Receptor | |
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ... | |||
T8708 | Paroxetine | Serotonin Transporter | |
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression. | |||
T22124 | Oleoyl Serotonin | TRP/TRPV Channel | |
Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM. | |||
T37015 | Iprindole | 5-HT Receptor | |
Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1]. | |||
T2209 | Serotonin hydrochloride | 5-HT hydrochloride,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride | 5-HT Receptor , Endogenous Metabolite , Transferase |
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM). | |||
T11075 | Donitriptan | 5-HT Receptor | |
Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and 5-HT1D, respectively. | |||
T8666 | Naratriptan | 5-HT Receptor | |
Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches. | |||
TN1969 | N-(p-Coumaroyl) serotonin | PDGFR | |
N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving... | |||
TN2437 | Serotonin | 5-hydroxytryptamine,5-HT | Others , 5-HT Receptor , Endogenous Metabolite , Transferase |
Serotonin (5-hydroxytryptamine) is a natural product from animals | |||
T2815 | Puerarin | Kakonein | 5-HT Receptor |
Puerarin (Kakonein), also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist. | |||
T28531 | Facinicline hydrochloride | RG3487 | 5-HT Receptor , AChR |
Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimot... | |||
T19680 | Zotepine | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor | |
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. Zotepine is a second... | |||
T2459 | BRL 54443 | BRL54443 | 5-HT Receptor |
BRL 54443 is a potent 5-HT1E/1F receptor agonist (pKi values are 8.7 and 8.9 respectively). | |||
T9113 | Myristicin | Myristicine | IL Receptor , Anti-infection , BCL , P450 , PARP , 5-HT Receptor , Caspase , GABA Receptor , NO Synthase |
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with ... | |||
T5387 | LP-211 | Dopamine Receptor , 5-HT Receptor | |
LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor. | |||
T2599 | Pirenperone | 5-HT Receptor | |
Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action. | |||
T0525 | Flopropione | Phloropropiophenone | 5-HT Receptor , Transferase |
Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist. | |||
T2428 | TG6-10-1 | 5-HT Receptor , Prostaglandin Receptor | |
TG6-10-1 is an EP2 antagonist. | |||
T0031L2 | Ziprasidone | Geodon,Zeldox,CP-88059 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Norepinephrine , Histamine Receptor |
Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity. |